Category Archives: Health

Egg Metabolites in Blood related to lower risk of type 2 Diabetes

Eggs remain one of the most controversial food items. High intake of eggs has traditionally been discouraged, mainly due to their high cholesterol content. However, eggs are also a rich source of many bioactive compounds that can have beneficial effects on health. This means that the health effects of consuming eggs are difficult to determine based solely on their cholesterol content.

The investigators have previously shown that eating roughly one egg per day was associated with a lower risk of developing type 2 diabetes among middle-aged men participating in the Kuopio Ischaemic Heart Disease Risk Factor Study in eastern Finland.

“The purpose of the current study was to explore potential compounds that could explain this association using non-targeted metabolomics, a technique that enables a broad profiling of chemicals in a sample,” says Early Stage Researcher and lead author of the study Stefania Noerman from the University of Eastern Finland.

The study found that the blood samples of men who ate more eggs included certain lipid molecules that positively correlated with the blood profile of men who remained free of type 2 diabetes. In addition, the researchers identified several biochemical compounds in blood that predicted a higher risk of developing type 2 diabetes, including the amino acid tyrosine.

The study suggests some plausible mechanisms which could at least partly explain the inverse association between egg intake and the previously observed lower risk of developing type 2 diabetes.

“Although it is too early to draw any causal conclusions, we now have some hints about certain egg-related compounds that may have a role in type 2 diabetes development. Further detailed investigations with both cell models and intervention studies in humans that use modern techniques, such as metabolomics, are needed to understand the mechanisms behind physiological effects of egg intake,” Early Stage Researcher Noerman concludes.

For further information, please contact:

Stefania Noerman, Early Stage Researcher, +358465270258, stefania.noerman@uef.fi

Kati Hanhineva, PhD, Adjunct Professor in Nutritional Metabolomics, +358403552364,kati.hanhineva@uef.fi

Jyrki Virtanen, PhD, Adjunct Professor in Nutritional Epidemiology, +358294454542,jyrki.virtanen@uef.fi

Institute of Public Health and Clinical Nutrition, University of Eastern Finland

Research article:
Metabolic profiling of high egg consumption and the associated lower risk of type 2 diabetes in middle-aged Finnish men.

Stefania Noerman, Olli Kärkkäinen, Anton Mattsson, Jussi Paananen, Marko Lehtonen, Tarja Nurmi, Tomi-Pekka Tuomainen, Sari Voutilainen, Kati Hanhineva, and Jyrki K Virtanen

Molecular Nutrition and Food Research, published online 12 December 2018

Many diseases increase the risks of hip fracture surgery

Parkinson’s disease, osteoarthritis, rheumatic diseases, alcoholism and mental health disorders increase the risk of surgical complications after a hip fracture surgery, a new Finnish study analysing nationwide registers finds. 4.6% of all hip surgery patients and 10% of total hip replacement surgery patients experienced surgical complications within three months following their surgery.

Postal code area data can help in the planning of cost-effective health care services

hen assessing the effects of socioeconomic status (SES) on health inequalities or outcomes of care, it is worthwhile to use small-area-based open data instead of individual SES information, a new study from the University of Eastern Finland shows. Getting access to individual SES information is often a long and expensive process, requiring many different permits. Published in BMC Public Health, the study found that when predicting the treatment outcomes in patients with type 2 diabetes, the effect of small-area-based SES variables is in line with patient-specific individual SES information.

Novel antibacterial drugs developed at University of Eastern Finland

Researchers at the University of Eastern Finland have developed novel antibacterial compounds, focusing on the role of LsrK kinase. LsrK kinase is a protein involved in bacterial communication. In a new study published in ChemMedChem, the researchers explore LsrK kinase as a target in antibacterial drug design.

In the era of increased antibiotic resistance, it is necessary to focus on developing new antibacterial agents. Rising resistance alarms us following the traditional mechanisms of antibiotics for drug development. Addressing this, the INTEGRATE consortium focused on validating novel targets that can be used in future antibacterial drug development. Quorum sensing (QS) is a process of bacterial communication involved in the host colonization, virulence factors production, biofilm formation and infection establishment. Consequently, the investigation of quorum quenching and inhibiting agents, which would interfere with the production and processing of QS mediators, has become a new strategy for developing antivirulence agents.

Doctors Separate Conjoined Twins At Abuja Hospital,speaker Dogara Pay The Bill

A set of conjoined twins(boys) have been separated by doctors at Gwagwalada Special Hospital.The surgery reported took place on Monday 29th of Oct 2018.The surgery cost N1m.

According to report,Speaker Dogara played a significant role in footing the bill of the surgery.Attention of Dogara was drawn to the condition of the twins when Ms Mariam Mohamed made a post about the conjoined twins.

Women Who Wear High Heels Risk Developing Arthritis –Physiotherapist

A physiotherapist, Mr. Vincent Shoetan, says women who wear high heeled shoes on a regular basis risk the chances of developing knee problems, including arthritis and back pains in future.

Shoetan, who spoke to the News Agency of Nigeria on Friday in Lagos, advised women, who want to wear high heeled shoes not to wear them for an extended period.

Scientists uncover why knee joint injury leads to osteoarthritis

University of Eastern Finland
Press release, 25 October 2018
Scientists uncover why knee joint injury leads to osteoarthritis

Knee joint injuries are typically related to sports, such as football, rugby or ice hockey, but people often do not know that such injuries may lead to joint inflammation and post-traumatic osteoarthritis. In advanced post-traumatic osteoarthritis, joint cartilage breaks down completely, causing severe joint pain, lack of mobility and even social isolation. However, the mechanisms leading to osteoarthritis are not known. Currently, it is not possible for a physician examining a patient to predict future joint condition and possible development of osteoarthritis. In the future, however, this may be possible, as a new study from the University of Eastern Finland and Massachusetts Institute of Technology now shows that articular cartilage degenerates specifically around injury areas when the fluid flow velocity becomes excessive. The findings were reported in Scientific Reports.

Lady Who Dramatically Changed Her Skin Color Through Tanning Injection Gets Married In Hawaii

Lady Who Dramatically Changed Her Skin Color Through Tanning Injection Gets Married In Hawaii

A glamour model who hit the spotlight after dramatically changing her skin colour through tanning injections has married in Hawaii.